Cyanidin-3- O -glucoside chloride inhibits cartilage degeneration and inflammation in TMJOA via YAP/NF-κB signaling pathway

Food & Function 2026

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Authors: Dongyang Li, Zhe Zhou, TIAN Wei, Jing Zhang, Jie Zhang, Kexin Huang, Xueyuan Han, Xiao Yuan, Chunmiao Jiang
DOI: 10.1039/d5fo04230e
Cited by: 0
References: 47

Abstract

. Collectively, these findings indicate that C3G confers protection against TMJOA by inhibiting cartilage matrix degradation, promoting extracellular matrix deposition, and suppressing inflammation through blockade of the YAP/NF-κB signaling axis, thereby highlighting C3G as a promising therapeutic candidate for the management of TMJOA.

Fields of Study & Subjects

Osteoarthritis Treatment and Mechanisms Natural Compounds in Disease Treatment Temporomandibular Joint Disorders

Publication details

Journal / source
Food & Function
Volume
17
Issue
5
Pages
2240–2251
Publication date
1 January 2026
Language
EN