Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability

Food & Function 2026 Open access

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Authors: María‐Teresa García‐Conesa, Rocío Garcı́a-Villalba, María Dolores Frutos-Lisón, Carlos Garcia, Javier Marhuenda, Pilar Zafrilla, Juan A. Tudela, Marta Ruiz Arráez, Gary Williamson, Carrie Ruxton, Francisco A. Tomás-Barberán
DOI: 10.1039/d5fo04536c
Cited by: 1
References: 54

Abstract

between 100% OJ and 0% OJ than 'low responders' as well as differences in the 60 min plasma metabolomes, particularly in OJ-derived metabolites like dihydroferulic acid glucuronide. The OJ fruit matrix attenuates postprandial glucose peaks and rate of glucose rise in healthy young males. The occurrence of responder groups with differentiated plasma metabolomes underscores the importance of considering both the food matrix and individual physiological differences when assessing the glycemic impact of fruit juices.

Fields of Study & Subjects

Diet Metabolism and Disease Food composition and properties Natural Antidiabetic Agents Studies

Publication details

Journal / source
Food & Function
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
5
Pages
2292–2310
Publication date
1 January 2026
Language
EN