Plum-derived exosome-like nanovesicles alleviate DSS-induced colitis through gut and liver protection

Food & Function 2026

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Authors: Hayeon Jang, Hyun-Jin Kim, Jae-Hee Kwon, Ji-Su Kim, Dong-Ha Kim, Sang-Hoon Lee, Seung-Hwan Heo, Bum-Joon Koo, Jihoon Kim, Wan-Kyu Lee, Kwang-Won Seo, Do-Kyun Kim
+1 more Young-Eun Cho
DOI: 10.1039/d5fo04597e
Cited by: 3
References: 40

Abstract

. Moreover, the PNVs inhibited oxidative stress marker proteins and significantly reduced DSS-induced intestinal permeability, endotoxemia, and inflammation-related bowel and liver damage. Therefore, this study suggests that PNVs may alleviate IBD and protect the gut-liver axis through their antioxidant and anti-inflammatory properties.

Fields of Study & Subjects

Extracellular vesicles in disease Barrier Structure and Function Studies Inflammatory Bowel Disease

Publication details

Journal / source
Food & Function
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
5
Pages
2599–2609
Publication date
1 January 2026
Language
EN