Theaflavins ameliorate obesity through enhanced antioxidant capacity, a suppressed hepatic BCAA degradation pathway, and gut microbiota modulation

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Authors: Ruili Pan, Ping Wu, YiFan Zhang, Xiaolei Shi, Yu Zhang, Dajiang Gu, Jin Zhao
Cited by: 0
References: 55

Abstract

). Correlation analysis integrated these findings, revealing significant associations between the TF-induced microbial shifts, the ameliorated metabolic phenotypes, and the suppressed hepatic BCAA catabolism. Our study demonstrated that the alleviation of obesity by TFs was associated with multifaceted improvements, including enhanced antioxidant capacity, amelioration of dysregulated hepatic BCAA catabolism, and modulation of gut microbial homeostasis, highlighting their potential as a dietary intervention for metabolic diseases.

Fields of Study & Subjects

Gut microbiota and health Tea Polyphenols and Effects Phytochemicals and Antioxidant Activities

Publication details

Journal / source
Food & Function
Volume
17
Issue
5
Pages
2521–2535
Publication date
1 January 2026
Language
EN