A randomised controlled study to investigate the cognitive, mood, metabolic and anti-inflammatory effects of chronic oyster mushroom intervention in healthy older adults

Food & Function 2026 Open access

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Authors: Sara Cha, Lynne Bell, Jessica Eastwood, D. R. Fisher, B. Shukitt-Hale, Zicheng Zhang, Ana Rodriguez‐Mateos, Claire M. Williams
DOI: 10.1039/d5fo04951b
Cited by: 1
References: 47

Abstract

rodent microglial cell model. After 12-weeks supplementation, the OM group outperformed the PL group in RAVLT delayed word recall and delayed word recognition and displayed lower negative mood, as indicated by PANAS-X sadness, PANAS-X shyness and DASS-21 anxiety. Overall, the 12-week OM intervention, maintained mood and improved episodic memory in older adults compared to PL, alongside reducing markers of inflammation.

Fields of Study & Subjects

Fungal Biology and Applications Antioxidants Aging Portulaca oleracea Medicinal Plants and Neuroprotection

Publication details

Journal / source
Food & Function
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
12
Pages
5621–5633
Publication date
1 January 2026
Language
EN