Lactoferrin protects against radiation-induced intestinal injury by regulating pyroptosis and mitophagy

Food & Function 2026

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Authors: Wenyue Shan, Wei Wei, Yuqi Zhang, Li-Li Zhang, Yu Zhao, Jia Li Gu, Le Zhao, Khemayanto Hidayat, Yulong Liu, Yu Chong, Lin Zhao, Liqiang Qin
+1 more Jiaying Xu
DOI: 10.1039/d5fo04989j
Cited by: 0
References: 60

Abstract

Lactoferrin protects against radiation-induced intestinal injury by regulating pyroptosis and mitophagy to clear damaged mitochondria, prevent mtROS/mtDNA leakage, suppresse NLRP3 inflammasome, reduce IL-1β/GSDMD cleavage and attenuate inflammation.

Fields of Study & Subjects

Infant Nutrition and Health Inflammasome and immune disorders Animal health and immunology

Publication details

Journal / source
Food & Function
Volume
17
Issue
2
Pages
1045–1060
Publication date
1 January 2026
Language
EN