The therapeutic mechanism of bornyl acetate in alleviating ulcerative colitis by regulating the intestinal flora

Food & Function 2026

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Authors: Bingqing Shang, minghui Yang, Liduan Yin, Suyuan Lv, Tong Wang, Qiu Wu, Yue Geng
DOI: 10.1039/d5fo05003k
Cited by: 1
References: 66

Abstract

was negatively correlated with p65 transcriptional activity in the NF-κB pathway but positively correlated with anti-inflammatory cytokine IL-10 and the mRNA levels of barrier proteins (ZO-1 and occludin). In conclusion, these findings indicated that BA alleviates UC through a synergistic mechanism encompassing NF-κB pathway inhibition, microbiota homeostasis restoration and intestinal barrier repair. This discovery offers a theoretical basis for novel functional foods leveraging terpenoids to restore gut microecological balance.

Fields of Study & Subjects

Inflammatory Bowel Disease Essential Oils and Antimicrobial Activity Pharmacological Effects of Medicinal Plants

Publication details

Journal / source
Food & Function
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
3
Pages
1500–1517
Publication date
1 January 2026
Language
EN