Dietary iron supplementation modulates thyroid immune homeostasis and ameliorates experimental autoimmune thyroiditis in mice

Food & Function 2026

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Authors: Yingjie Chen, Chunmei Wang, Qi-Lan Jiang, Tao Li, Jun Jiang
DOI: 10.1039/d5fo05210f
Cited by: 0
References: 62

Abstract

: Our findings demonstrate that dietary iron supplementation promotes regulatory immune responses and attenuates autoimmune thyroiditis, highlighting the functional significance of adequate dietary iron intake in maintaining thyroid immune homeostasis. These results provide experimental support for dietary iron optimization as a potential nutritional approach for AITD prevention.

Fields of Study & Subjects

Thyroid Disorders and Treatments Iron Metabolism and Disorders T-cell and B-cell Immunology

Publication details

Journal / source
Food & Function
Volume
17
Issue
6
Pages
2893–2906
Publication date
1 January 2026
Language
EN