Lessons learned on how to reengineer enzymes for improved performance in ionic liquids: insights from BSLA saturation mutagenesis library

Green Chemistry 2026 Open access

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Authors: Shuaiqi Meng, Yu Ji, Maxine Yew, Leilei Zhu, Ulrich Schwaneberg
DOI: 10.1039/d5gc04809e
Cited by: 1
References: 79

Abstract

Based on a complete BSLA saturation mutagenesis library, this review shows how ionic liquids reshape enzyme solvation and performance. Preserving and modulating the hydration shell emerges as a key design principle for IL-tolerant biocatalysts.

Fields of Study & Subjects

Enzyme Catalysis and Immobilization Ionic liquids properties and applications Microbial metabolism and enzyme function

Publication details

Journal / source
Green Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
28
Issue
11
Pages
4705–4714
Publication date
1 January 2026
Language
EN