Spatial organization of an enzyme cascade in a Ni-ZIF-8 framework for efficient sugar nucleotide synthesis

Green Chemistry 2026

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Authors: Youbo Yu, Xingcheng Zhou, Lisha Yan, Li Yang, Jie Hong, Krongthong Kamonsuangkasem, Peiyi Wang, WMWW Kandegama, Gefei Hao, Libo Zhang
DOI: 10.1039/d5gc06007a
Cited by: 1
References: 70

Abstract

The Ni-ZIF-8 nanocomposite spatially organizes a dual-enzyme conjugate, achieving highly enhanced activity and a channeling-like effect for efficient UDP-GlcNAc synthesis.

Fields of Study & Subjects

Metalloenzymes and iron-sulfur proteins Enzyme Catalysis and Immobilization Microbial Metabolic Engineering and Bioproduction

Publication details

Journal / source
Green Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
28
Issue
10
Pages
4474–4489
Publication date
1 January 2026
Language
EN