Metabolic, redox, and spatial engineering of Yarrowia lipolytica for high-level zeaxanthin production

Green Chemistry 2026

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Authors: Lingxuan Sun, Jin Zhang, Haotian Zhai, Huangwei Xu, Mengmeng Liu, Qingsheng Qi, Jin Hou
DOI: 10.1039/d5gc06011g
Cited by: 5
References: 51

Abstract

Yarrowia lipolytica was engineered through an integrated metabolic engineering strategy that couples genetic, redox, and spatial regulation, enabling zeaxanthin overproduction at 6.9 g L −1 the highest reported titer to date.

Fields of Study & Subjects

Microbial Metabolic Engineering and Bioproduction Enzyme Catalysis and Immobilization Biochemical and biochemical processes

Publication details

Journal / source
Green Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
28
Issue
4
Pages
2087–2097
Publication date
1 January 2026
Language
EN