Mn-catalyzed hydroxyalkylation of α-trifluoromethylstyrenes with cyclopropanols: facile synthesis of δ-trifluoromethyl-δ-hydroxyketones

Green Chemistry 2026

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Authors: Zhixin Deng, Zhigang Liu, Jiyao Han, Tong-Yao Zhou, Dang Cheng, Xiao XIAO, Fen‐Er Chen
DOI: 10.1039/d5gc06095h
Cited by: 11
References: 104

Abstract

A concise and efficient hydroxyalkylation of cyclopropanols with α-(trifluoromethyl)alkenes enables the economic and green construction of valuable δ-trifluoromethyl-δ-hydroxyketones under mild conditions with broad substrate scope.

Fields of Study & Subjects

Fluorine in Organic Chemistry Cyclopropane Reaction Mechanisms Carbon dioxide utilization in catalysis

Publication details

Journal / source
Green Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
28
Issue
12
Pages
5447–5456
Publication date
1 January 2026
Language
EN