Metal- and photosensitizer-free hydrodifluoromethylation of unactivated alkenes via acetamide-activated difluoromethyl aryl sulfones

Green Chemistry 2026

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Authors: Lujun Lou, Tianshuai Zhu, Jing-Jing Zhang, Zhen Jia Chen
DOI: 10.1039/d5gc06124e
Cited by: 5
References: 87

Abstract

Herein, we report a photocatalyst- and metal-free, visible-light-induced hydrodifluoromethylation of unactivated alkenes via an acetamide-mediated activation of difluoromethyl aryl sulfones, a class of bench-stable CF 2 H reagents.

Fields of Study & Subjects

Fluorine in Organic Chemistry Radical Photochemical Reactions Sulfur-Based Synthesis Techniques

Publication details

Journal / source
Green Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
28
Issue
10
Pages
4515–4524
Publication date
1 January 2026
Language
EN