Microfluidic capillary transit velocity as a functional measure for sickle cell disease and in vitro -derived red blood cells

Lab on a Chip 2026 Open access

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Authors: Solomon Oshabaheebwa, Utku Goreke, Yong Du, Christopher L. Wirth, Zoe Sekyonda, Bryan L. Benson, Payam Fadaei, Yusang B. Ley, Nathan M Perez, Petros Giannikopoulos, David N. Nguyen, Michael A. Suster
+2 more Pedram Mohseni, Umut Atakan Gurkan
DOI: 10.1039/d5lc00769k
Cited by: 1
References: 58

Abstract

This study presents a biomimetic microfluidic assay to evaluate the capillary transit velocity of red blood cells at single-cell resolution, highlighting heterogeneity and therapeutic effects in sickle cell disease and in vitro derived cells.

Fields of Study & Subjects

Hemoglobinopathies and Related Disorders Blood properties and coagulation Erythrocyte Function and Pathophysiology

Publication details

Journal / source
Lab on a Chip
Publisher
Royal Society of Chemistry (RSC)
Volume
26
Issue
4
Pages
976–990
Publication date
1 January 2026
Language
EN