Lateral flow biosensors for low abundance detection of brain natriuretic peptide with enzyme-free amplification
Abstract
a lateral flow test (LFT) format, providing visual readouts close to the patient in 30 min at room temperature. This work advances the field by combining the specificity of aptamers with the simplicity of LFTs, offering the sensitivity of conventional immunoassays while eliminating any enzymatic steps. This work bridges the gap between lab-based immunoassays and POC needs, offering a reliable, equipment-free alternative for heart failure diagnosis in resource-limited settings. Future studies will validate its performance with blood samples for clinical deployment.
Fields of Study & Subjects
Advanced biosensing and bioanalysis techniques
Biosensors and Analytical Detection
Analytical Chemistry and Sensors
Publication details
- Journal / source
- Lab on a Chip
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 26
- Issue
- 3
- Pages
- 627–634
- Publication date
- 1 January 2026
- Language
- EN