Quasi-isostructural order–disorder phase transitions and anisotropic thermal expansions in polymorphic crystals of a biologically active molecule with distinct solubility and dissolution rate
Abstract
Dimorphs of a quinolone-amide-based bioactive molecule undergo isosymmetric order–disorder quasi-isostructural phase transitions at low temperatures and exhibit unusual thermal expansions. Form II has a faster dissolution rate and higher solubility.
Fields of Study & Subjects
Crystallization and Solubility Studies
Crystallography and molecular interactions
Solid-state spectroscopy and crystallography
Publication details
- Journal / source
- Materials Advances
- Volume
- 7
- Issue
- 6
- Pages
- 3177–3190
- Publication date
- 1 January 2026
- Language
- EN