Efficient log P determination by automated, spatially encoded 19 F NMR spectroscopy

RSC Medicinal Chemistry 2026 Open access

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Authors: Susanna H. Wood, Fiona Gordon, Robin S. Stein, Mark J. Howard, John A. Parkinson
DOI: 10.1039/d5md00678c
Cited by: 0
References: 31

Abstract

A method for measuring log P of fluorinated molecules by 19 F NMR under full instrument automation. Placing an advanced NMR technique in the hands of synthetic chemists for simple, efficient data acquisition.

Fields of Study & Subjects

Advanced NMR Techniques and Applications Molecular spectroscopy and chirality Fluorine in Organic Chemistry

Publication details

Journal / source
RSC Medicinal Chemistry
Volume
17
Issue
3
Pages
1550–1558
Publication date
1 January 2026
Language
EN