Prodrug strategies in developing antiviral nucleoside analogs

RSC Medicinal Chemistry 2026 Open access

Read full text
Authors: R. Rama Suresh, Tuniyazi Abuduani, Mahesh Kasthuri, Zhe Chen, Zahira Tber, Mohammed Loubidi, Hu Zhang, Longhu Zhou, Shaoman Zhou, C Li, Amita Kumari, Sijia Tao
+4 more John M. Wiseman, Selwyn J. Hurwitz, Franck Amblard, Raymond F. Schinazi
DOI: 10.1039/d5md00810g
Cited by: 6
References: 124

Abstract

Prodrug strategies are used to enhance the physicochemical and pharmaceutical properties of drug candidates that may not be suitable for specific delivery or are limited by formulation options.

Fields of Study & Subjects

HIV/AIDS drug development and treatment Biochemical and Molecular Research Click Chemistry and Applications

Publication details

Journal / source
RSC Medicinal Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
1
Pages
105–131
Publication date
1 January 2026
Language
EN