Microwave-assisted single-step synthesis of cyclic and acyclic β-aminosulfones and evaluation of their antifungal activity targeting CYP51

RSC Medicinal Chemistry 2026 Open access

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Authors: Abigail Bibiana Pinheiro, Soumik Saha, Madhuri Madduri, Utpal Roy, Lakshmi Sudhir Menon, Sumit Biswas, Amrita Chatterjee, Mainak Banerjee
DOI: 10.1039/d5md00907c
Cited by: 1
References: 45

Abstract

), the spot test revealed insignificant inhibition. Cytotoxicity studies with selected molecules revealed that these aza-sulfones are non-toxic to human cells, encouraging further studies with β-aminosulfone scaffolds.

Fields of Study & Subjects

Sulfur-Based Synthesis Techniques Microwave-Assisted Synthesis and Applications Organic and Inorganic Chemical Reactions

Publication details

Journal / source
RSC Medicinal Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
2
Pages
1083–1098
Publication date
1 January 2026
Language
EN