1,3,4-Oxadiazole derivatives: targeting multiple bacterial pathways

RSC Medicinal Chemistry 2026 Open access

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Authors: Pankaj Gupta, Sangeeta Verma, Rakesh Narang, Bhupesh K. Sharma, Vikramjeet Singh, Sukhbir Lal
DOI: 10.1039/d5md01139f
Cited by: 1
References: 172

Abstract

The present study consolidates recent advances in SAR analysis and various binding modes of 1,3,4-oxadiazole derivatives as antibacterial agents, published between 2021 and 2025. This information will be beneficial for researchers in the development of novel antibacterial molecules based on the 1,3,4-oxadiazole moiety.

Fields of Study & Subjects

Synthesis and biological activity Antimicrobial agents and applications Structural and Chemical Analysis of Organic and Inorganic Compounds

Publication details

Journal / source
RSC Medicinal Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
17
Issue
4
Pages
1867–1887
Publication date
1 January 2026
Language
EN