Harnessing oligonucleotide architecture for potent multivalent inhibition of human carbonic anhydrases

RSC Medicinal Chemistry 2026 Open access

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Authors: Eslam M. Abbass, Federico Ladu, Justine Mansot, Mathieu Noël, Alessio Nocentini, Mario Sechi, Claudiu Trandafir Supuran, Michaël Smietana, Jean‐Yves Winum
DOI: 10.1039/d5md01167a
Cited by: 0
References: 27

Abstract

This study introduces oligonucleotides as spatially defined multivalent platforms for carbonic anhydrase inhibitor design.

Fields of Study & Subjects

Enzyme function and inhibition Advanced biosensing and bioanalysis techniques DNA and Nucleic Acid Chemistry

Publication details

Journal / source
RSC Medicinal Chemistry
Volume
17
Issue
4
Pages
1961–1967
Publication date
1 January 2026
Language
EN