Mechanochemical synthesis of aspirin nanocrystals for pharmaceutical applications

RSC Mechanochemistry 2026 Open access

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Authors: G.D.S Kanchana Garumanna, Ranjit Thakuria, Nadeesh Madusanka Adassooriya
DOI: 10.1039/d5mr00118h
Cited by: 0
References: 35

Abstract

Aspirin nanocrystals were synthesized via mechanochemical milling following the standardization of key processing parameters. The resulting nanocrystallization led to a significant enhancement in the oral bioavailability of aspirin.

Fields of Study & Subjects

Drug Solubulity and Delivery Systems Crystallization and Solubility Studies Mineral Processing and Grinding

Publication details

Journal / source
RSC Mechanochemistry
Volume
3
Issue
3
Pages
393–401
Publication date
1 January 2026
Language
EN