High-throughput C–H activation in a bead-beater homogenizer: fast and regioselective access to 2-arylindoles

RSC Mechanochemistry 2026 Open access

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Authors: Mainak Banerjee, B. Shravya, Aboy Chatterjee, Shamima Hussain, Amrita Chatterjee
DOI: 10.1039/d5mr00124b
Cited by: 0
References: 58

Abstract

This work demonstrates the utility of a bead-beater homogenizer for high-throughput mechanosynthesis (HTMS), exemplified by Pd( ii )-catalyzed C2-H arylation of indoles in simple polypropylene vials with SS balls, affording products in just 9 min.

Fields of Study & Subjects

Crystallography and molecular interactions Supramolecular Chemistry and Complexes Axial and Atropisomeric Chirality Synthesis

Publication details

Journal / source
RSC Mechanochemistry
Volume
3
Issue
2
Pages
309–315
Publication date
1 January 2026
Language
EN