Anti-inflammatory effects of curcumin carbon dots in an animal model of demyelination induced by lysolecithin
Abstract
anti-inflammatory and neuroprotective effects were evaluated in C57BL/6 male mice subjected to demyelination through local lysolecithin injection. Histological analyses showed reduced myelin loss and preserved myelin basic protein levels in animals treated with CurP-CDs compared to controls at 3 and 7 days post-lysolecithin injection. In addition, immunostaining revealed decreased astrocyte and microglia activation, the leading cells in neuroinflammation and gliosis, indicating reduced inflammation.
Fields of Study & Subjects
Curcumin's Biomedical Applications
Silymarin and Mushroom Poisoning
Advanced Drug Delivery Systems
Publication details
- Journal / source
- Nanoscale Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 8
- Issue
- 6
- Pages
- 1888–1898
- Publication date
- 1 January 2026
- Language
- EN