Effect of single xeno-nucleic acid replacement on the fluorescence of DNA-encapsulated silver nanoclusters

Nanoscale Advances 2026 Open access

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Authors: Hari Chandana Yadavalli, Riddhi Nagda, Jooyoun Kang, Minhaeng Cho, Chenguang Lou, Seong Wook Yang, Peter Waaben Thulstrup, Morten Jannik Bjerrum, Pratik Shah
DOI: 10.1039/d5na00862j
Cited by: 0
References: 29

Abstract

The fluorescent properties of DNA/AgNCs are largely governed by the composition of AgNCs, the nucleobase sequence, and the secondary structure of the DNA template. Here, by systematic incorporation of xeno-nucleic acid modifications, we demonstrate the potential of altering the sugar chemistry of the template DNA backbone, as a novel factor in AgNC fluorescence modulation.

Fields of Study & Subjects

Nanocluster Synthesis and Applications Gold and Silver Nanoparticles Synthesis and Applications Advanced biosensing and bioanalysis techniques

Publication details

Journal / source
Nanoscale Advances
Volume
8
Issue
4
Pages
1191–1196
Publication date
1 January 2026
Language
EN