Nanoparticle ultrastructure allows reversible pH sensitivity using 19 F NMR and in vivo 19 F MRI

Nanoscale Advances 2026 Open access

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Authors: Alvja Mali, Mariah R. R. Daal, Natalia Ziółkowska, Nicolas Stumpe, Naiara Larreina Vicente, N. Koen van Riessen, Visakh V. S. Pillai, Francesco Simone Ruggeri, Cyril Cadiou, Françoise Chuburu, Daniel Jirák, Paul B. White
+1 more Mangala Srinivas
DOI: 10.1039/d5na01005e
Cited by: 2
References: 66

Abstract

F MRI probes for imaging applications in tumours and other pH-sensitive disease environments. It demonstrates, for the first time, PRE-driven signal enhancement and suppression governed by structural rearrangement rather than chemical modification in response to pH variation.

Fields of Study & Subjects

Lanthanide and Transition Metal Complexes Advanced MRI Techniques and Applications Advanced NMR Techniques and Applications

Publication details

Journal / source
Nanoscale Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
8
Issue
6
Pages
1975–1991
Publication date
1 January 2026
Language
EN