Impact of protein corona on magnetic particle spectroscopy-based bioassays

Nanoscale Advances 2026 Open access

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Authors: Gabrielle Rose Moss, Christian Knopke, Solomon Diamond
DOI: 10.1039/d5na01037c
Cited by: 2
References: 45

Abstract

We prepared a homogenous assay consisting of biotinylated magnetic nanoparticles that target streptavidin. Our assay's measurable concentration range shifted to lower streptavidin concentrations in the presence of low affinity off-target protiens.

Fields of Study & Subjects

Nanoparticle-Based Drug Delivery Characterization and Applications of Magnetic Nanoparticles Protein Interaction Studies and Fluorescence Analysis

Publication details

Journal / source
Nanoscale Advances
Publisher
Royal Society of Chemistry (RSC)
Volume
8
Issue
5
Pages
1543–1555
Publication date
1 January 2026
Language
EN