CaCO 3 -assisted engineering of NIR-II phototheranostics enables photothermally enhanced ferroptosis in cancer through synergistically depleting intracellular glutathione

Nanoscale Horizons 2026

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Authors: Juxin Gao, Hengze Ding, Qinghua Wu, Yuhang Hu, Yifan Yan, Minming Chen, Chunjie Wang, Zhuang Liu, Liangzhu Feng
DOI: 10.1039/d5nh00664c
Cited by: 1
References: 30

Abstract

Ca NPs achieved substantial tumor suppression in mouse models, with a complete remission rate of 80%. This study establishes a facile strategy for developing long-circulating NIR-II phototheranostic agents with self-amplified lipid peroxidation induction capacity, enabling photothermally augmented ferroptosis for cancer therapy.

Fields of Study & Subjects

Nanoplatforms for cancer theranostics Ferroptosis and cancer prognosis Sulfur Compounds in Biology

Publication details

Journal / source
Nanoscale Horizons
Publisher
Royal Society of Chemistry (RSC)
Volume
11
Issue
4
Pages
1071–1080
Publication date
1 January 2026
Language
EN