Simultaneous detection of lymphocytes and tumor cells in vivo in response to STING-TLR9 immunotherapy with Raman active multiplexed gold nanostars

Nanoscale Horizons 2026 Open access

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Authors: Siddhant Kothadiya, Gabriel Cutshaw, Ansuja Pulickal Mathew, Casey Zielinski, Rizia Bardhan
DOI: 10.1039/d5nh00687b
Cited by: 1
References: 46

Abstract

Multiplexed gold nanostars enable in vivo and ex vivo SERS imaging of CD8 + T cells and VEGFR2 + tumor cells capturing dynamic T cell recruitment and vascular changes in the tumor to enable treatment response to immunotherapy.

Fields of Study & Subjects

interferon and immune responses Nanowire Synthesis and Applications Nanoplatforms for cancer theranostics

Publication details

Journal / source
Nanoscale Horizons
Publisher
Royal Society of Chemistry (RSC)
Volume
11
Issue
3
Pages
865–882
Publication date
1 January 2026
Language
EN