Nanoscale opportunities in extracellular matrix mimicry
Abstract
We present an overview of the composition, function, energetics, and dynamics of extracellular matrix and its relation to nanoscale structures and phenomena. These concepts are then related to the development of synthetic and biosynthetic materials that aim to mimic the extracellular matrix for regenerative medicine and tissue engineering technologies. Notable successes and advancements towards the goal of biomimicry are outlined, while remaining challenges and knowledge gaps towards that goal are highlighted. Finally, we frame the remaining challenges in the field in terms of nanoscience-related research opportunities that if solved, might prove to be transformative steps forward in the discipline.
Fields of Study & Subjects
Tissue Engineering and Regenerative Medicine
Electrospun Nanofibers in Biomedical Applications
Hydrogels: synthesis
properties
applications
Publication details
- Journal / source
- Nanoscale Horizons
- Volume
- 11
- Issue
- 5
- Pages
- 1178–1191
- Publication date
- 1 January 2026
- Language
- EN