Facile synthesis of 2-anilinonicotinic acids via Cu–Mg–Al LDO catalysed amination of 2-chloronicotinic acid

New Journal of Chemistry 2026

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Authors: Shashikant Sampat Gholap, Abhimanyu K. Yadav, Parul Khurana
DOI: 10.1039/d5nj03368c
Cited by: 3
References: 48

Abstract

This work illustrates an efficient and green synthetic route for the preparation of pharmaceutical compounds—specifically Clonixin, Flunixin, and Niflumic acid—using a recyclable and reusable Cu–Mg–Al LDO catalyst in ethanol under heating conditions.

Fields of Study & Subjects

Catalytic Cross-Coupling Reactions Coordination Chemistry and Organometallics Synthesis and Characterization of Pyrroles

Publication details

Journal / source
New Journal of Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
50
Issue
10
Pages
4305–4311
Publication date
1 January 2026
Language
EN