Solvent directed base-enabled diastereodivergent domino cycloaddition of isoxazole–oxindole styrenes and Michael additions of isoxazole–styrenes with vinyl malononitriles
Abstract
A base-catalyzed strategy for the diastereodivergent synthesis of complex spirocyclic oxindoles and linear Michael's adducts are disclosed.
Fields of Study & Subjects
Asymmetric Synthesis and Catalysis
Organic Chemistry Synthesis Methods
Organic Chemistry Cycloaddition Reactions
Publication details
- Journal / source
- New Journal of Chemistry
- Volume
- 50
- Issue
- 5
- Pages
- 2350–2355
- Publication date
- 1 January 2026
- Language
- EN