Piperidinium borate as an efficient and recyclable catalyst for one-pot, three-component, environmentally friendly synthesis of pyran-annulated heterocycles and 2-amino-3-cyano-4 H -pyrans
Abstract
Piperidinium boratecatalysed a one-pot three-component Knoevenagel and Michael-type addition reaction to give pyrazoles/pyrimidinone/2-amino-3-cyano-4 H -pyrans. This study highlights benefits of method, showing high atom economy and reaction mass efficiency and low E -factor.
Fields of Study & Subjects
Multicomponent Synthesis of Heterocycles
Synthesis of heterocyclic compounds
Synthesis and biological activity
Publication details
- Journal / source
- New Journal of Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 50
- Issue
- 6
- Pages
- 2846–2853
- Publication date
- 1 January 2026
- Language
- EN