The development of novel AIE-active staurosporine-based fluorescent probes with theranostic potential

New Journal of Chemistry 2026

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Authors: Nannan Chen, Yuqiu Ye, Longfeng Zhang, Xia Wang, Shijie Liu, Xiaoming Chen, Tong Wu, Jingming Zhou, Haipeng Xu, Lijun Xie
DOI: 10.1039/d5nj03817k
Cited by: 0
References: 39

Abstract

Three AIE-active staurosporine derivatives were designed and synthesized, which retain antitumor activity and exhibit fluorescence within tumor cells, making them promising candidates for fluorescent probes in cancer diagnosis and therapy.

Fields of Study & Subjects

Luminescence and Fluorescent Materials Molecular Sensors and Ion Detection Synthesis and biological activity

Publication details

Journal / source
New Journal of Chemistry
Volume
50
Issue
4
Pages
1982–1989
Publication date
1 January 2026
Language
EN