DBU-promoted [3+2] cycloaddition for the synthesis of trispiro heterocycles from acetylpyrazolyl-substituted oxindoles and substituted isatins

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Authors: Yun-Qing Jia, Ting-Ting Mu, Hongxian Liu, Min Xiang, Li-Wen Shen
Cited by: 2
References: 42

Abstract

DBU-promoted [3+2] annulation of 3-pyrazolyl oxindoles with isatins constructs privileged 3,3′-polyspiro oxindole-γ-butyrolactones, featuring mild conditions, broad scope, and scalability.

Fields of Study & Subjects

Synthesis and Characterization of Pyrroles Synthesis and Reactivity of Heterocycles Catalytic C–H Functionalization Methods

Publication details

Journal / source
New Journal of Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
50
Issue
9
Pages
3947–3951
Publication date
1 January 2026
Language
EN