Diversity of enzymatic SAM-dependent C -methylation of aromatic compounds
Abstract
-monomethylation of ubiquitous molecules such as L-tyrosine to geminal dimethylation of complex polyketides resulting in dearomatization. This comprehensive review highlights the diversity of aromatic SAM-dependent MTs, their versatile substrates, and the resulting natural products.
Fields of Study & Subjects
Microbial Natural Products and Biosynthesis
Enzyme Structure and Function
Epigenetics and DNA Methylation
Publication details
- Journal / source
- Natural Product Reports
- Publisher
- Royal Society of Chemistry (RSC)
- Publication date
- 1 January 2026
- Language
- EN