Magnetic particle imaging lymphography (MPIL): a technique for lymph node mapping
Abstract
at the latest timepoint. This suggests similar SLN accumulation at early timepoints and higher accumulation at the late timepoint. Synomag-D70 PEG and Synomag-D70 PEG-mannose had more rapid clearance from the injection site compared to plain Synomag. The MPI signal was detected in higher echelon nodes (HENs) for all Synomag particles, with Synomag-D70 PEG-mannose having the lowest HEN signal at 24 hours. Overall, the mannose targeted version of Synomag met more of the criteria for what is considered a good tracer for SLNB, with higher clearance, accumulation and specificity compared to the other SPIONs tested in this study.
Fields of Study & Subjects
Characterization and Applications of Magnetic Nanoparticles
Electrical and Bioimpedance Tomography
Atomic and Subatomic Physics Research
Publication details
- Journal / source
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Volume
- 18
- Issue
- 6
- Pages
- 3018–3031
- Publication date
- 1 January 2026
- Language
- EN