An 124 I-radiolabeled exosome-based treatment platform for enhanced boron neutron capture therapy: precise delivery and real-time PET tracking of boron

Nanoscale 2026

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Authors: Ziteng Chen, Zhijie Wang, Mingxin Yang, Ruyu Yan, Linwen Lv, Yanan Chang, Kui Chen, Wenjiang Yang, Hui Yuan, Xiangxi Meng, Lingbo Zhu, Zhi Yang
+2 more Gengmei Xing, Juan Li
DOI: 10.1039/d5nr04823k
Cited by: 1
References: 37

Abstract

I-labeled BCDs into a large excess of unlabeled BCDs, followed by exosome encapsulation. This approach offers a practical and clinically translatable strategy for real-time treatment guidance. This study provides a generalizable technical paradigm for advancing exosome-mediated BNCT toward clinical application in gliomas.

Fields of Study & Subjects

Boron Compounds in Chemistry Boron and Carbon Nanomaterials Research Organoboron and organosilicon chemistry

Publication details

Journal / source
Nanoscale
Publisher
Royal Society of Chemistry (RSC)
Volume
18
Issue
12
Pages
6564–6575
Publication date
1 January 2026
Language
EN