TfOH-triggered denitrogenative union of diazo carbonyl compounds and indolin-2-thiones toward functionalized indole derivatives and their preliminary anticancer assessment

Organic & Biomolecular Chemistry 2026

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Authors: Sakshi Haridas Sable, S S S S Sudha Ambadipudi, Sai Balaji Andugulapati, Alagesan Balasubramani
DOI: 10.1039/d5ob01227a
Cited by: 1
References: 47

Abstract

]indoles, through a cascade process involving S-H insertion, cyclization, and dehydration. Furthermore, these newly synthesized compounds showed promising anti-cancer activities against breast cancer and prostate cancer cell models.

Fields of Study & Subjects

Cyclopropane Reaction Mechanisms Catalytic C–H Functionalization Methods Click Chemistry and Applications

Publication details

Journal / source
Organic & Biomolecular Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
24
Issue
8
Pages
1697–1702
Publication date
1 January 2026
Language
EN