A gold( iii )-catalyzed Conia-ene reaction for the direct synthesis of substituted pyrroles from β-ketopropargyl amines

Organic & Biomolecular Chemistry 2026 Open access

Read full text
Authors: Sayed Mustafa Badr, Mustafa Durmaz, Nurettin Mengeş
DOI: 10.1039/d5ob01665g
Cited by: 2
References: 24

Abstract

We disclose a gold-catalyzed conversion of unactivated β-ketopropargyl amines to polysubstituted pyrroles under mild, operationally simple conditions. This protocol was further extended to synthesize indolizine skeleton via a one-pot process.

Fields of Study & Subjects

Catalytic Alkyne Reactions Synthesis and Characterization of Pyrroles Catalytic C–H Functionalization Methods

Publication details

Journal / source
Organic & Biomolecular Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
24
Issue
11
Pages
2219–2224
Publication date
1 January 2026
Language
EN