Chemoselective synthesis of multi-functionalized alkynes and alkenes via transition-metal-free iodination of terminal alkynes
Abstract
/KI reagent system in water under ultrasonication. Chemoselectivity has been achieved by a judicious choice of the reaction conditions for synthesizing monoiodination and diiodination products. This diversity-oriented synthesis requires no purification, allowing access to a variety of compounds in pure forms in excellent yields. The reactions are compatible with many substrates, and practical applications are demonstrated with a scale-up reaction.
Fields of Study & Subjects
Oxidative Organic Chemistry Reactions
Click Chemistry and Applications
Catalytic Alkyne Reactions
Publication details
- Journal / source
- Organic & Biomolecular Chemistry
- Volume
- 24
- Issue
- 5
- Pages
- 1016–1020
- Publication date
- 1 January 2026
- Language
- EN