Synthesis of α-alkenylated nitriles via electrochemical generation of ketyl radicals
Abstract
An electrochemical α-alkenylation of nitriles was developed in an undivided cell under base-free conditions. A wide range of nitriles and aldehydes were effectively converted into the corresponding α-alkenylated derivatives with high yields by virtue of this method. The reaction features broad substrate scope, metal-free and chemical oxidant-free conditions, and scalability.
Fields of Study & Subjects
Radical Photochemical Reactions
Oxidative Organic Chemistry Reactions
Sulfur-Based Synthesis Techniques
Publication details
- Journal / source
- Organic & Biomolecular Chemistry
- Volume
- 24
- Issue
- 6
- Pages
- 1346–1351
- Publication date
- 1 January 2026
- Language
- EN