TMEDA-catalyzed synthesis of pentasubstituted 2-aminopyrroles from ynehydrazides and dialkyl acetylenedicarboxylates

Organic & Biomolecular Chemistry 2026

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Authors: Zhiwei Zeng, Jingwei Lin, Yongchao Xie, Jiangbin Guo, Nan Ma, Jian Lei, Lin JinGuo, Xiaolan Xie
DOI: 10.1039/d5ob01825k
Cited by: 0
References: 35

Abstract

cyclization, providing a rapid and modular route to the target scaffolds in moderate to high yields. Furthermore, an integrated approach for the direct conversion of simple terminal alkynes into the target pyrroles was devised, facilitating efficient access to these complex structures.

Fields of Study & Subjects

Synthesis and Characterization of Pyrroles Catalytic Alkyne Reactions Catalytic Cross-Coupling Reactions

Publication details

Journal / source
Organic & Biomolecular Chemistry
Volume
24
Issue
5
Pages
1011–1015
Publication date
1 January 2026
Language
EN