Photoredox-catalyzed Giese reaction for the synthesis of γ-nitro alcohols

Organic & Biomolecular Chemistry 2026

View at publisher
Authors: Ai-Jie He, Wen-Jie Jiang, Yan-Ping Zhang, Lei Yang, Jian‐Qiang Zhao, Zhen-Hua Wang, Wei‐Cheng Yuan, Yong You
DOI: 10.1039/d5ob01840d
Cited by: 1
References: 44

Abstract

A photoredox-catalyzed Giese reaction of (trimethylsilyl)methanol with nitroalkenes has been developed, providing convenient access to γ-nitro alcohols, which are valuable precursors to 1,3-amino alcohols.

Fields of Study & Subjects

Radical Photochemical Reactions Chemical Synthesis and Reactions Sulfur-Based Synthesis Techniques

Publication details

Journal / source
Organic & Biomolecular Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
24
Issue
5
Pages
1042–1047
Publication date
1 January 2026
Language
EN