Cu-catalyzed N–S bond coupling between hydroxylamines and sulfinic acids: rapid access to N -arylsulfonamides

Organic & Biomolecular Chemistry 2026

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Authors: Lin Zhu, Yang Wang, Han Guo, Rui Liu, Yu Wang, Meng-Yun Dang, Feng-Lan Hu, Wen-Jun Han, Jun‐Long Zhan, Yunhe Lv
DOI: 10.1039/d5ob01851j
Cited by: 1
References: 56

Abstract

-arylsulfonamides without additional oxidants has been demonstrated. The protocol features the advantages of operational simplicity, environmental friendliness and mild reaction conditions. Mechanistic studies have shown that hydroxylamine exhibits unique multifunctionality in this reaction, serving as a reducing reagent, an amine donor, and a potential oxidant.

Fields of Study & Subjects

Sulfur-Based Synthesis Techniques Catalytic C–H Functionalization Methods Catalytic Cross-Coupling Reactions

Publication details

Journal / source
Organic & Biomolecular Chemistry
Publisher
Royal Society of Chemistry (RSC)
Volume
24
Issue
5
Pages
1021–1026
Publication date
1 January 2026
Language
EN