Four-component assembly of polysubstituted pyrimidines via dual C(sp 3 )–H functionalization of primary aliphatic amines

Organic & Biomolecular Chemistry 2026

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Authors: Kang Liu, Jiaoling Li, Sichen Xu, Xi Zhang, Peng Xue, Yao‐Fu Zeng, Xinping Liu, Ying Hong Peng, Zhen Wang, Jinjin Chen
DOI: 10.1039/d5ob01866h
Cited by: 0
References: 63

Abstract

An efficient iodine-promoted four-component reaction has been developed for the synthesis of diverse polysubstituted pyrimidines via dual C(sp 3 )–H functionalization of primary aliphatic amines.

Fields of Study & Subjects

Catalytic C–H Functionalization Methods Multicomponent Synthesis of Heterocycles Synthesis and Characterization of Pyrroles

Publication details

Journal / source
Organic & Biomolecular Chemistry
Volume
24
Issue
5
Pages
995–999
Publication date
1 January 2026
Language
EN