Facile one-pot synthesis of 5-alkylidene-2,3,5,6,7,8-hexahydroimidazo[1,2- a ]pyridines
Abstract
A new methodology for the synthesis of unknown 5-alkylidene-2,3,5,6,7,8-hexahydroimidazo[1,2- a ]pyridines is reported through the intramolecular cyclization of linear bis-α,β-alkynic ketone precursors via an imidazoline intermediate.
Fields of Study & Subjects
Synthesis of heterocyclic compounds
Synthesis and Reactions of Organic Compounds
Multicomponent Synthesis of Heterocycles
Publication details
- Journal / source
- Organic & Biomolecular Chemistry
- Volume
- 24
- Issue
- 12
- Pages
- 2522–2531
- Publication date
- 1 January 2026
- Language
- EN