Reformulating lumefantrine as Flash NanoPrecipitated particles and the impact of incorporation into milk-based formulations on drug solubilisation during digestion

RSC Pharmaceutics 2026 Open access

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Authors: Malinda Salim, Kurt D. Ristroph, Thomas Eason, Gisela Ramirez, Andrew J. Clulow, Robert K. Prud’homme, Ben J. Boyd
DOI: 10.1039/d5pm00294j
Cited by: 0
References: 22

Abstract

Digestion of infant formula enabled the solubilisation of lumefantrine, which was greatly enhanced when the drug was formulated as nanoparticles in an amorphous form.

Fields of Study & Subjects

Drug Solubulity and Delivery Systems Pharmaceutical studies and practices Nanoparticle-Based Drug Delivery

Publication details

Journal / source
RSC Pharmaceutics
Volume
3
Issue
2
Pages
564–573
Publication date
1 January 2026
Language
EN