Mechanistic investigation of the denitrosylation activity of a water-soluble copper( ii ) compound probed by experimental and computational approaches

Inorganic Chemistry Frontiers 2026

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Authors: Bruna B. Segat, Adolfo Horn, Bruno Szpoganicz, Lino Meurer, Roberta Cargnelutti, Rodrigo Cervo, Luis Gabriel Wagner, Sreerag N. Moorkkannur, Rajeev S. Prabhakar, Pinheiro, Lucas Cézar, 1986-, Siti Noriza Kamel, Sumeet Mahajan
+2 more Martin Feelisch, Christiane Fernandes
DOI: 10.1039/d5qi02129d
Cited by: 1
References: 41

Abstract

A water-soluble Cu( ii ) compound promotes the denitrosylation of GSNO at room temperature and physiological pH. A reaction mechanism was proposed based on kinetic, spectroscopic, and spectrometric experiments, further supported by DFT calculations.

Fields of Study & Subjects

Metal-Catalyzed Oxygenation Mechanisms Nitric Oxide and Endothelin Effects Metal complexes synthesis and properties

Publication details

Journal / source
Inorganic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
7
Pages
2976–2988
Publication date
1 January 2026
Language
EN