Synthesis of quinazolinone scaffolds from the cascade reaction of o -aminobenzamides/ o -aminobenzonitriles and calcium carbide mediated by K 2 S

Organic Chemistry Frontiers 2026

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Authors: Shuyi Li, Yunzhe Du, Ligang Yan, Siliu Cheng, Shuang Cao, Ruijun Xie, Limin Han, Ning Zhu
DOI: 10.1039/d5qo01490e
Cited by: 2
References: 49

Abstract

K 2 S-mediated one-pot synthesis of quinazolinones or dihydroquinazolinones from o -aminobenzamides (or o -aminobenzonitriles) and calcium carbide offers a cost-effective and sustainable alternative.

Fields of Study & Subjects

Quinazolinone synthesis and applications Multicomponent Synthesis of Heterocycles Synthesis and bioactivity of alkaloids

Publication details

Journal / source
Organic Chemistry Frontiers
Publisher
Royal Society of Chemistry (RSC)
Volume
13
Issue
5
Pages
1578–1585
Publication date
1 January 2026
Language
EN